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Collection:
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NASA Marshall Space Flight Center Collection
Collection
NASA Marshall Space Flight Center Collection
Collection
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Name of Image:
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Computer-generated Model of Purine Nucleoside Phosphorylase (PNP)
Name_of_Image
Computer-generated Model of Purine Nucleoside Phosphorylase (PNP)
Name of Image
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Full Description:
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Purine Nucleoside Phosphorylase (PNP) is an important target enzyme for the design of anti-cancer and immunosuppressive drugs. Bacterial PNP, which is slightly different from the human enzyme, is used to synthesize chemotherapuautic agents. Knowledge of the three-dimensional structure of the bacterial PNP molecule is useful in efforts to engineer different types of PNP enzymes, that can be used to produce new chemotherapeutic agents. This picture shows a computer model of bacterial PNP, which looks a lot like a display of colorful ribbons. Principal Investigator was Charles Bugg.
Full_Description
Purine Nucleoside Phosphorylase (PNP) is an important target enzyme for the design of anti-cancer and immunosuppressive drugs. Bacterial PNP, which is slightly different from the human enzyme, is used to synthesize chemotherapuautic agents. Knowledge of the three-dimensional structure of the bacterial PNP molecule is useful in efforts to engineer different types of PNP enzymes, that can be used to produce new chemotherapeutic agents. This picture shows a computer model of bacterial PNP, which looks a lot like a display of colorful ribbons. Principal Investigator was Charles Bugg.
Full Description
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Date of Image:
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1987-02-01
Date_of_Image
1987-02-01
Date of Image
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Category:
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Microgravity
Category
Microgravity
Category
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(MRPO) MRD-SPD Discipline(s):
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Biotechnology
(MRPO)_MRD-SPD_Disci pline(s)
Biotechnology
(MRPO) MRD-SPD Discipline(s)
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(MRPO) Subject Type:
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Science
(MRPO)_Subject_Type
Science
(MRPO) Subject Type
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term:
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Microgravity
Keywords
Microgravity
term
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term:
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Science
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term:
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PCG Computer Modeling
Keywords
PCG Computer Modeling
term
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facet_what:
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Cancer
facet_what
Cancer
facet_what
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facet_where:
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Marshall Space Flight Center (MSFC)
facet_where
Marshall Space Flight Center (MSFC)
facet_where
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Reference Number:
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MSFC-75-SA-4105-2C
Reference_Number
MSFC-75-SA-4105-2C
Reference Number
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MIX #:
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8772406
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NIX #:
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MSFC-8772406
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MSFC Negative Number:
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8772406
MSFC_Negative_Number
8772406
MSFC Negative Number
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UID:
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SPD-MARSH-8772406
UID
SPD-MARSH-8772406
UID
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original url:
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original_url
original url
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