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Collection:
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NASA Marshall Space Flight Center Collection
Collection
NASA Marshall Space Flight Center Collection
Collection
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Name of Image:
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Colon tumor cells grown in NASA Bioreactor
Name_of_Image
Colon tumor cells grown in NASA Bioreactor
Name of Image
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Full Description:
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These photos compare the results of colon carcinoma cells grown in a NASA Bioreactor flown on the STS-70 Space Shuttle in 1995 flight and ground control experiments. The cells grown in microgravity (left) have aggregated to form masses that are larger and more similar to tissue found in the body than the cells cultured on the ground (right). The principal investigator is Milburn Jessup of the University of Texas M. D. Anderson Cancer Center. The NASA Bioreactor provides a low turbulence culture environment which promotes the formation of large, three-dimensional cell clusters. Due to their high level of cellular organization and specialization, samples constructed in the bioreactor more closely resemble the original tumor or tissue found in the body. NASA-sponsored bioreactor research has been instrumental in helping scientists to better understand normal and cancerous tissue development. In cooperation with the medical community, the bioreactor design is being used to prepare better models of human colon, prostate, breast and ovarian tumors. Cartilage, bone marrow, heart muscle, skeletal muscle, pancreatic islet cells, liver and kidney are just a few of the normal tissues being cultured in rotating bioreactors by investigators. Cell constructs grown in a rotating bioreactor on Earth (left) eventually become too large to stay suspended in the nutrient media. In the microgravity of orbit, the cells stay suspended. Rotation then is needed for gentle stirring to replenish the media around the cells. The work is sponsored by NASA's Office of Biological and Physical Research. The bioreactor is managed by the Biotechnology Cell Science Program at NASA's Johnson Space Center (JSC). Credit: NASA and University of Texas M. D. Anderson Cancer Center.
Full_Description
These photos compare the results of colon carcinoma cells grown in a NASA Bioreactor flown on the STS-70 Space Shuttle in 1995 flight and ground control experiments. The cells grown in microgravity (left) have aggregated to form masses that are larger and more similar to tissue found in the body than the cells cultured on the ground (right). The principal investigator is Milburn Jessup of the University of Texas M. D. Anderson Cancer Center. The NASA Bioreactor provides a low turbulence culture environment which promotes the formation of large, three-dimensional cell clusters. Due to their high level of cellular organization and specialization, samples constructed in the bioreactor more closely resemble the original tumor or tissue found in the body. NASA-sponsored bioreactor research has been instrumental in helping scientists to better understand normal and cancerous tissue development. In cooperation with the medical community, the bioreactor design is being used to prepare better models of human colon, prostate, breast and ovarian tumors. Cartilage, bone marrow, heart muscle, skeletal muscle, pancreatic islet cells, liver and kidney are just a few of the normal tissues being cultured in rotating bioreactors by investigators. Cell constructs grown in a rotating bioreactor on Earth (left) eventually become too large to stay suspended in the nutrient media. In the microgravity of orbit, the cells stay suspended. Rotation then is needed for gentle stirring to replenish the media around the cells. The work is sponsored by NASA's Office of Biological and Physical Research. The bioreactor is managed by the Biotechnology Cell Science Program at NASA's Johnson Space Center (JSC). Credit: NASA and University of Texas M. D. Anderson Cancer Center.
Full Description
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Date of Image:
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2001-05-15
Date_of_Image
2001-05-15
Date of Image
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Category:
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Microgravity
Category
Microgravity
Category
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(MRPO) MRD-SPD Discipline(s):
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Biotechnology
(MRPO)_MRD-SPD_Disci pline(s)
Biotechnology
(MRPO) MRD-SPD Discipline(s)
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(MRPO) Subject Type:
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Science
(MRPO)_Subject_Type
Science
(MRPO) Subject Type
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term:
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BIOREACTOR
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facet_what:
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Earth
facet_what
Earth
facet_what
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facet_what:
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Cancer
facet_what
Cancer
facet_what
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facet_what:
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Space Shuttle Orbiter
facet_what
Space Shuttle Orbiter
facet_what
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facet_where:
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Texas
facet_where
Texas
facet_where
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facet_where:
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Marshall Space Flight Center (MSFC)
facet_where
Marshall Space Flight Center (MSFC)
facet_where
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facet_where:
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Johnson Space Center (JSC)
facet_where
Johnson Space Center (JSC)
facet_where
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facet_when:
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1995
facet_when
1995
facet_when
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facet_when_year:
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1995
facet_when_year
1995
facet_when_year
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Reference Number:
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MSFC-75-SA-4105-2C
Reference_Number
MSFC-75-SA-4105-2C
Reference Number
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MIX #:
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0101743
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NIX #:
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MSFC-0101743
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MSFC Negative Number:
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0101743
MSFC_Negative_Number
0101743
MSFC Negative Number
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UID:
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SPD-MARSH-0101743
UID
SPD-MARSH-0101743
UID
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original url:
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original_url
original url
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